Mark Twain is a documentary film on the life of Mark Twain also known as Samuel Clements produced by Ken Burns in 2001. Burns captures both the public and private persona of Mark Twain from his birth to his death. The film was narrated by Keith David and the voice of Mark Twain was provided by Kevin Conway.

Keith David, Kevin Conway, Philip Bosco, Blythe Danner, Tim Clark, Carolyn McCormick, Amy Madigan, Cynthia Nixon, John Boyer, Jocelyn Chadwick, Shelly Fisher Fishkin, Dick Gregory, Hal Holbrook, Chuck Jones, Arthur Miller, Ron Powers, Laura Skandera-Trombley, William Styron